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The eMC  

Last Updated 13 Jul 2015

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Deflazacort 6mg tablets

Deflazacort (Def-flazza-cort) is a medicine which is used in situations wherecorticosteroid treatmentis necessary.

The information in this Medicine Guide for Deflazacort varies according to the condition being treated and the particular preparation used.

Deflazacort 6mg tablets

Information specific to Deflazacort 6mg tablets when used in situations where corticosteroid treatment is necessary

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Your medicine

Deflazacort is a corticosteroid. Deflazacort works by preventing or reducing inflammation. It is used to treat a number of conditions that are characterised by excessive inflammation.

Deflazacort suppresses the immune system and so can be used to treat autoimmune diseases. Deflazacort can help to prevent and to treat the rejection of transplanted organs. It can also be used in the treatment of certain types of cancers.

People who take corticosteroids for a long period of time are prone to infections as their immune system can become weak. These infections may be much more severe than they usually would be and the symptoms that would usually be used to identify such infections can be hidden. For this reason people who take Deflazacort must be careful to avoid exposure to infections such as chickenpox and measles whenever possible. If you have been exposed to chickenpox or measles, you must get immediate medical advice. You should continue to take your medicine unless your prescriber advises you to stop taking it.

Other information about Deflazacort:

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

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When to take your medicine

Some medicines work best if they are taken at a specific time of day. Getting the most benefit from your medicine can also be affected by what you eat, when you eat and the times at which you take other medicines.

Specific information on when to take Deflazacort can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. You can also ask your doctor or pharmacist for information about when to take your medicine.

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How to take your medicine

Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine.

Specific information on how to take Deflazacort can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to take your medicine from your doctor or pharmacist.

If you are having problems taking this form of Deflazacort, you should talk to your prescriber or pharmacist. They may be able to give you advice on other ways to take your medicine or other preparations that are easier for you to take.

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Taking too much of your medicine

Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. You may need a test to assess the effect of taking extra doses. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice.

Contact your prescriber, pharmacist, specialist clinic or call 111 for advice.

Make sure you take all of your medicine containers with you if you are advised to go to hospital.

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Stopping your medicine

If you are not having any problems taking this medicine then do not stop taking it, even if you feel better, unless advised to do so by your prescriber. If, however, you find that this medicine is causing you problems then you should talk to your prescriber about your concerns.

If your medical team decides that it is best that you do not take this medicine any more, they may advise that you do not stop Deflazacort abruptly. This is because, in some instances, stopping Deflazacort abruptly can cause withdrawal symptoms or cause your original condition to return. In these instances, reducing the dose of Deflazacort gradually over time may reduce the chances of having these problems.

If you are in any doubt, contact your prescriber, pharmacist, specialist clinic or call 111.

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Looking after your medicine

The instructions on how you should keep your medicine are on the pharmacy label. It is a good idea to keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children.

Specific information on how to look after Deflazacort can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to look after your medicine from your doctor or pharmacist.

You must not take the medicine after the expiry date shown on the packaging. If you have any unused medicine, return it to your pharmacist who will dispose of it safely.

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Whether this medicine is suitable for you

Deflazacort is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child.

Over time it is possible that Deflazacort can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Deflazacort has become unsuitable, it is important that the prescriber is contacted immediately.

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A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Common: More than 1 in 100 people who take Deflazacort:

  • psychiatric or psychological problems such as; feeling irritable; depression; mood swings; euphoria; thoughts of committing suicide; psychotic reactions; mania; delusions; hallucination; worsening of schizophrenia; behavioural disturbances; feeling anxious; sleep disturbances; memory problems or confusion. You or your carer must seek medical advice if you develop any of these symptoms. Psychiatric or psychological problems may also occur when stopping Deflazacort
  • weight gain

Uncommon: More than 1 in 1000 people who take Deflazacort:

  • acne
  • adrenal problems these may be fatal
  • amenorrhoea
  • bleeding
  • bone fractures
  • cushingoid facies
  • hair overgrowth
  • headaches
  • hypersensitivity reactions including anaphylaxis
  • increased risk of getting infections which may become severe - some of these such as chickenpox may be fatal. If you get any symptoms of an infection or are exposed to chickenpox, you must immediately seek medical advice
  • indigestion
  • nausea
  • oedema
  • osteoporosis
  • peptic ulcers with perforation
  • raised blood pressure with sodium and water retention
  • reactivation of tuberculosis
  • reduced carbohydrate tolerance with an increased requirement for antidiabetic therapy
  • striae
  • vertigo

Rare: More than 1 in 10,000 people who take Deflazacort:

The frequency of these side-effects is unknown:

  • abnormal laboratory test results
  • appetite gain
  • blood problems
  • cataracts - these may develop if Deflazacort is taken for a long period of time
  • diabetes in the elderly
  • eye or eyesight problems
  • feeling restless
  • glaucoma - this may happen if Deflazacort is taken for a long period of time
  • growth suppression in infants, children and adolescents
  • healing problems
  • heart problems
  • hiding symptoms of infection
  • increased pressure in the eye
  • intracranial hypertension
  • irregular menstrual periods
  • metabolic problems
  • muscle problems
  • osteonecrosis
  • pancreatitis
  • papilloedema
  • raised intracranial pressure in children
  • telangiectasia
  • thinning of the skin
  • thromboembolism
  • withdrawal symptoms can occur when this medicine is stopped. These include fever, muscle pain or tenderness, joint pain, rhinitis, conjunctivitis, weight loss or painful itchy skin. If the dose of Deflazacort is reduced too rapidly serious problems can occur including adrenal problems, lowered blood pressure or death
  • worsening of epilepsy
  • worsening of eye infections

The following side effects have been reported in people who have had medicines similar to Deflazacort. The frequency of these side-effects in people who take Deflazacort is not known:

  • tendon inflammation
  • tendon rupture

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.

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Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Deflazacort:

The following types of medicine may interact with Deflazacort:

If you are taking Deflazacort and one of the above medicines or types of medicines, make sure your prescriber knows about it.

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Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Deflazacort.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Deflazacort:

  • this medicine is unlikely to affect driving ability or the ability to operate machinery
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Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Deflazacort:

  • while you are taking Deflazacort your prescriber may advise you to limit the amount of salt and potassium supplements in your diet

If your diet includes any of the above, speak to your prescriber or pharmacist for further advice.

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Alcohol can interact with certain medicines.

In the case of Deflazacort:

  • there are no known interactions between alcohol and Deflazacort
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Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Deflazacort:

  • you should only take this medicine during pregnancy if your doctor thinks that you need it
  • if you take this medicine during your pregnancy, your baby may have some problems after birth

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Deflazacort, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

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Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Deflazacort:

  • you should only take this medicine while breast-feeding if your doctor thinks you need it

Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. You should only breast-feed your baby while taking this medicine on the advice of your doctor or midwife.

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Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's taste and appearance and to make it easier to take. Some may be used to prolong the life of the medicine.

This medicine contains deflazacort.

We are unable to list all of the ingredients for your medicine here. For a full list, you should refer to the patient information leaflet that comes with this medicine. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies. You should also check whether any of these ingredients are known to have side-effects.

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Deflazacort before, do not take Deflazacort. Talk to your prescriber, pharmacist or nurse as soon as possible.

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Deflazacort, Version 10, last updated 13 Jul 2015