- 1. Name of the medicinal product
- 2. Qualitative and quantitative composition
- 3. Pharmaceutical form
- 4. Clinical particulars
- 4.1 Therapeutic indications
- 4.2 Posology and method of administration
- 4.3 Contraindications
- 4.4 Special warnings and precautions for use
- 4.5 Interaction with other medicinal products and other forms of interaction
- 4.6 Fertility, pregnancy and lactation
- 4.7 Effects on ability to drive and use machines
- 4.8 Undesirable effects
- 4.9 Overdose
- 5. Pharmacological properties
- 5.1 Pharmacodynamic properties
- 5.2 Pharmacokinetic properties
- 5.3 Preclinical safety data
- 6. Pharmaceutical particulars
- 6.1 List of excipients
- 6.2 Incompatibilities
- 6.3 Shelf life
- 6.4 Special precautions for storage
- 6.5 Nature and contents of container
- 6.6 Special precautions for disposal and other handling
- 7. Marketing authorisation holder
- 8. Marketing authorisation number(s)
- 9. Date of first authorisation/renewal of the authorisation
- 10. Date of revision of the text
Murine irritation & redness relief
Naphazoline Hydrochloride 0.012 %w/v
Also contains Benzalkonium Chloride
For full list of excipients, see section 6.1
Eye drops solution (eye drops)
Clear, colourless liquid.
Redness and minor irritations of the eye caused by, for example, dusty atmosphere, wind, swimming, smoke, air pollutants, and close work.
Adults and children 12 years and over
The recommended dosage is one or two drops into each eye two or three times daily.
Children under 12 years: Not recommended. There is no recorded experience with the product in this age group.
Glaucoma, corneal damage, acute iritis and other serious eye disease.
Hypersensitivity to any ingredients.
Do not use at the same time as contact lenses. It is generally recommended that a short interval be allowed between the use of Murine and replacement of contact lenses, and that the duration of this 'short interval' should be about 15 minutes.
This product should not be used prior to peripheral iridectomy in eyes susceptible to angle closure because mydriatic action may precipitate angle block.
Murine should not be used if there is an eye condition characterised by continued redness, pain or blurring of vision.
Murine should not be used if there is raised pressure inside the eyeball (glaucoma), damage to the corneas, inflammation of the iris (acute iritis) or any other serious eye disease.
If there is any eye pain, vision changes, continued redness or irritation of the eye, or if the condition worsens or persists for more than 24 hours, use of the product should be discontinued and the doctor or pharmacist should be informed.
Discontinue use prior to use of anaesthetics which sensitise the myocardium to sympathomimetics (e.g. cyclopropane, halothane).
As with other sympathomimetics, use with caution in the presence of hypertension, diabetes, hyperthyroidism, cardiovascular abnormalities and arteriosclerosis.
Contains benzalkonium chloride which may cause eye irritation. Avoid contact with soft contact lenses; remove contact lenses prior to application and wait at least 15 minutes before re-insertion; known to discolour soft contact lenses.
Currently there is no information regarding the use of Murine and the absorption of concomitant ocular products. However, patients should be advised to leave a short interval between the administration of Murine and other ocular products. It is generally recommended that this interval should be of about 15 minutes duration.
No special precautions.
Do not drive or operate machinery if vision is blurred.
May cause slight dilation of pupil.
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system:
Yellow Card Scheme: Website: www.mhra.gov.uk/yellowcard
Overdosage or accidental administration by mouth may cause depression of CNS, reduction of body temperature, bradycardia, sweating, drowsiness and coma, particularly in children. Hypertension may be followed by rebound hypotension. In addition, overdosage may cause increased redness of the eye. Treatment of side-effects is symptomatic.
ATC Code: S01GA01
Naphazoline is a sympathomimetic agent with marked alpha-adrenergic activity. It is a vasoconstrictor with a rapid and prolonged action in reducing swelling and congestion when applied to mucous membrane.
Absorbed following instillation into conjunctival sacs.
There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SmPC.
Benzalkonium chloride, boric acid (E284), borax (E285), purified water and disodium edetate.
Unopened: 36 months.
Opened: 1 month.
Do not store above 25°C.
5 ml of liquid in a LDPE bottle fitted with a LDPE drop-forming plug and a polypropylene cap.
10 ml of liquid in a HDPE bottle fitted with a LDPE/DPE drop-forming plug and a polypropylene cap.
Do not use if the solution changes colour or becomes cloudy.
Prestige Brands (UK) Limited
46 High Street
15 October 2003
14th July 2017
Prestige Brands (UK) Ltd
46 High Street, Yatton, Somerset, BS49 4HJ
+44 (0)1934 838870
+44 (0)1934 838820