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Adalat retard 20 mg modified-release tablets

Last Updated on eMC 30-Sep-2016 View document  | Bayer plc Contact details

When a pharmaceutical company changes an SPC or PIL, a new version is published on the eMC.  For each version, we show the dates it was published on the eMC and the reasons for change.

Updated on 30-Sep-2016 and displayed until Current

Reasons for adding or updating:

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.6 - Fertility, pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 5.2 - Pharmacokinetic properties
  • Change to section 10 - Date of revision of the text

Date of revision of text on the SPC: 19-Sep-2016

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

The key changes are:

To implement nifedipine CCDS changes and therefore update information related to patients with hepatic impairment in the SmPC; add changes resulting from a new pharmacokinetic study.

Updated on 23-Aug-2016 and displayed until 30-Sep-2016

Reasons for adding or updating:

  • Change to section 4.6 - Fertility, pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text

Date of revision of text on the SPC: 10-Aug-2016

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:



The key changes are:
Implementation of Adalat PSUSA EMA/394060/2016 outcome, i
nclusion of information on tocolytic use in pregnant women, SmPC sections 4.6 and 4.8 updated and PIL section 4.

Updated on 20-Aug-2015 and displayed until 23-Aug-2016

Reasons for adding or updating:

  • Change to section 2 - Qualitative and quantitative composition
  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.6 - Fertility, pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 6.3 - Shelf life
  • Change to section 10 - Date of revision of the text

Date of revision of text on the SPC: 05-Aug-2015

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:



The key changes are:

·        To update sections 2., 4.2, 4.3, 4.4, 4.6, 4.8, 5.1 and 6.3 of the SmPC in line with QRD template. 

Updated on 03-Feb-2014 and displayed until 20-Aug-2015

Reasons for adding or updating:

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.6 - Fertility, pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text

Date of revision of text on the SPC: 22-Jan-2014

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:



Changes to sections 4.2 (Posology and method of administration), 4.3 (Contraindications), 4.4 (Special warnings and precautions for use), 4.6 (Pregnancy and Lactation) and 4.8 (Undesirable effects), in line with the agreed CSP resulting from the Nifedipine PSUR Workshare. 

Updated on 21-Dec-2012 and displayed until 03-Feb-2014

Reasons for adding or updating:

  • Change to section 7 - Marketing authorisation holder

Date of revision of text on the SPC: 12-Apr-2012

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

Delete the "Bayer Schering Pharma" Logo.

Updated on 16-Apr-2012 and displayed until 21-Dec-2012

Reasons for adding or updating:

  • Change to section 7 - Marketing Authorisation Holder
  • Change to section 10 date of revision of the text

Date of revision of text on the SPC: 12-Apr-2012

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:



The key changes to the SmPCs are:

·        The statement 'Trading as Bayer plc, Bayer Schering Pharma' has been removed from Section 7 of the SmPC. 

Updated on 07-Mar-2012 and displayed until 16-Apr-2012

Reasons for adding or updating:

  • Change to section 10 date of revision of the text

Date of revision of text on the SPC: 16-Jan-2012

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

The key changes are:
  • Update to section 10 " Date of revision of the text". 

Updated on 15-Feb-2012 and displayed until 07-Mar-2012

Reasons for adding or updating:

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.8 - Undesirable Effects
  • Change to section 10 date of revision of the text

Date of revision of text on the SPC: 24-Nov-2011

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

The key changes are:

  • to update sections 4.2 (Posology and method of administration) and 5.1 (Pharmacodynamic properties) of the SmPC in line the overall conclusion and recommendation from an Art 45 EU worksharing procedure; with consequential changes to the PIL.
  • a separate update to section 4.8 (Undesirable effects) in line with the CCDS; with consequential changes to the PIL.

Updated on 23-Jul-2010 and displayed until 15-Feb-2012

Reasons for adding or updating:

  • Change to section 6. 3 - Shelf Life
  • Change to section 6. 5 - Nature and Contents of Container
  • Change to section 10 date of revision of the text

Date of revision of text on the SPC: 02-Jul-2010

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:



The key changes are:

  • change to section 6.3 to remove the information on the shelf-life of product packaged in PVC blister strips;
  • change to section 6.5 to remove the description of the PVC blister strip.

Updated on 01-Jul-2010 and displayed until 23-Jul-2010

Reasons for adding or updating:

  • Change to section 1 -Name of the Medicinal product
  • Change to section 6.1 - List of Excipients
  • Change to section 10 date of revision of the text

Date of revision of text on the SPC: 04-Jun-2010

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

Section 1 ( Product Name) : This has been amended to add the strength and pharmaceutical form to the product name, in line with the current SPC guideline.
Section 6.1 ( List of excipients): this section has been updated to bring the names of excipients in line the European Pharmacopoeia
Section 10 (Revision date) this is now 4 June 2010

Updated on 17-Sep-2009 and displayed until 01-Jul-2010

Reasons for adding or updating:

  • Change to section 6. 3 - Shelf Life
  • Change to section 10 date of revision of the text

Date of revision of text on the SPC: 09-Sep-2009

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

Section 6.3 - shelf life has been extended from 30 months to 48 months.
Section 10 - Revision date is now 09.09.2009

Updated on 03-Jun-2008 and displayed until 17-Sep-2009

Reasons for adding or updating:

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.3 - Contraindications
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 4.8 - Undesirable Effects
  • Change to section 5.1 - Pharmacodynamic Properties
  • Change to section 5.3 - Preclinical Safety Data
  • Change to section 10 date of revision of the text
  • Change to section 4.4 - Special warnings and precautions for Use
  • Change to section 4.6 - Pregnancy and Lactation
  • Change to section 5.2 - Pharmacokinetic Properties

Date of revision of text on the SPC: 22-May-2008

Legal Category:POM

Black Triangle (CHM): NO

Free-text change information supplied by the pharmaceutical company:

Sections 4.2, 4.3, 4.4, 4.5, 4.6, 4.8, 5.1, 5.2 and 5.3 have been updated following global labelling harmonisation in line with the Company Core Data Sheet. 

Updated on 29-Jun-2005 and displayed until 03-Jun-2008

Reasons for adding or updating:

  • Individual SPC superseded by joint SPC covering several presentations
  • Change to section 6. 5 - Nature and Contents of Container
  • Change to section 10 (date of (partial) revision of the text

Updated on 19-Dec-2003 and displayed until 29-Jun-2005

Reasons for adding or updating:

  • Change to section 4.2 - Posology and Method of Administration
  • Change to section 4.5 - Interactions with other Medicaments and other forms of Interaction
  • Change to section 4.8 - Undesirable Effects

Updated on 04-Sep-2003 and displayed until 19-Dec-2003

Reasons for adding or updating:

  • Improved Electronic Presentation

Updated on 03-Sep-2003 and displayed until 04-Sep-2003

Reasons for adding or updating:

  • New SPC for eMC ie an SPC for an existing product, but one that is new for the eMC

Company contact details

Company image
Address

Bayer House, Strawberry Hill, Newbury, Berkshire, RG14 1JA

Fax

+44 (0)1635 563 393

Telephone

+44 (0)1635 563 000

Before you contact this company: often several companies will market medicines with the same active ingredient. Please check that this is the correct company before contacting them. Why?

Active ingredients

nifedipine

Legal categories

POM - Prescription Only Medicine

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