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The eMC  

Last Updated 05 Jan 2015

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Rotigotine 2mg/24hours transdermal patches

Rotigotine (Ro-ti-go-tin) is a medicine which is used in Parkinson's disease and restless legs syndrome.

The information in this Medicine Guide for Rotigotine varies according to the condition being treated and the particular preparation used.

There are 4 preparations of Rotigotine available. If Rotigotine 2mg/24hours transdermal patches is not the preparation you are looking for, please select from the drop down list below.

Select your preparation (type) of Rotigotine

Rotigotine 2mg/24hours transdermal patches

Information specific to Rotigotine 2mg/24hours transdermal patches when used in Parkinson's disease

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Your medicine

Rotigotine activates certain types of nerves in the brain. It is used to treat Parkinson's disease.

Other information about Rotigotine:

  • your doctor may start you on a low dose of this medicine and then increase the dose depending on how you respond to treatment

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should use. It also tells you how often you should use your medicine. This is the dose that you and your prescriber have agreed you should use. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

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When to take your medicine

Some medicines work best if they are taken at a specific time of day. Getting the most from your medicine can also be affected by the times at which you take other medicines.

Specific information on when to use Rotigotine can be found in the Patient Information Leaflet that comes with this medicine. Alternatively, you can request information about when to take your medicine from your doctor or pharmacist.

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How to take your medicine

Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine.

Specific information on how to use Rotigotine can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to take your medicine from your doctor or pharmacist.

If you are having problems taking this form of Rotigotine, you should talk to your prescriber or pharmacist. They may be able to give you advice on other ways to take your medicine or other preparations that are easier for you to take.

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Taking too much of your medicine

Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice.

Contact your prescriber, pharmacist, specialist clinic or call 111 for advice.

Make sure you take all of your medicine containers with you if you are advised to go to hospital.

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Stopping your medicine

If you are not having any problems taking this medicine then do not stop using it, even if you feel better, unless advised to do so by your prescriber. If, however, you find that this medicine is causing you problems then you should talk to your prescriber about your concerns.

If your medical team decides that it is best that you do not take this medicine any more, they may advise that you do not stop Rotigotine abruptly. This is because, in some instances, stopping Rotigotine abruptly can cause withdrawal symptoms or cause your original condition to return. In these instances, reducing the dose of Rotigotine gradually over time may reduce the chances of having these problems.

If you are in any doubt, contact your prescriber, pharmacist, specialist clinic or call 111.

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Looking after your medicine

The instructions on how you should keep your medicine are on the pharmacy label. It is a good idea to keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children.

Specific information on how to look after Rotigotine can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to look after your medicine from your doctor or pharmacist.

You must not take the medicine after the expiry date shown on the packaging. If you have any unused medicine, return it to your pharmacist who will dispose of it safely.

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Whether this medicine is suitable for you

Rotigotine is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

  • to check that this medicine is not having any undesired effects

Over time it is possible that Rotigotine can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Rotigotine has become unsuitable, it is important that the prescriber is contacted immediately.

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A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Very common: More than 1 in 10 people who use Rotigotine:

  • application site reactions including hypersensitivity reactions or skin problems such as redness, rashes, itching, irritation, burning sensations, dermatitis, inflammation, swelling, eczema, skin lesions, exfoliation, urticaria or pain - seek medical advice if you get a rash or if the irritation spreads, worsens or is bothersome. You should avoid exposing irritated areas of the skin to direct sunlight as this can lead to skin colour changes
  • feeling dizzy
  • headaches
  • nausea
  • sleepiness - this may be excessive or occur very suddenly at any time of day. If this happens you must seek medical advice
  • vomiting

Common: More than 1 in 100 people who use Rotigotine:

  • a drop in blood pressure on standing or sitting up - this may lead to dizziness
  • abnormal laboratory test results
  • abnormal muscle movements or problems controlling muscle movement
  • behavioural changes such as an urge to perform tasks repeatedly, an urge to gamble, to buy or to shop, increased libido, hypersexuality, an unusual increase in appetite or binge eating. You or your carer should seek medical advice if there are any changes to your behaviour
  • changes in awareness
  • constipation
  • difficulty sleeping
  • dry mouth
  • fainting or brief loss of consciousness
  • falls
  • hallucinations
  • hiccups
  • increased sweating
  • indigestion
  • itching
  • lethargy
  • nightmares
  • oedema of the extremities
  • palpitations
  • raised blood pressure
  • redness of the skin
  • sleeping problems
  • strange dreams
  • vertigo
  • weakness including tiredness or a general feeling of being unwell
  • weight loss

Uncommon: More than 1 in 1000 people who use Rotigotine:

Rare: More than 1 in 10,000 people who use Rotigotine:

The frequency of these side-effects is unknown:

  • neuroleptic malignant-like syndrome - this has been reported in people who have suddenly stopped taking medicines similar to Rotigotine
  • retroperitoneal fibrosis or lung problems - these problems have been reported in people who have taken medicines similar to Rotigotine
  • thinking problems

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.

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Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Rotigotine:

The following types of medicine may interact with Rotigotine:

If you are taking Rotigotine and one of the above medicines or types of medicines, make sure your prescriber knows about it.

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Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Rotigotine.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Rotigotine:

  • this medicine could affect your ability to drive or operate machinery

Some people who take this medicine may have sudden attacks of sleepiness. You must not drive if you have had any sudden attacks of sleepiness caused by Rotigotine.

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery.

If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

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Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Rotigotine:

  • there are no specific foods that you must exclude from your diet when using Rotigotine
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Alcohol can interact with certain medicines.

In the case of Rotigotine:

You should seek advice from your prescriber as to whether you may drink alcohol while taking this medicine.

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Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Rotigotine:

  • do not use this medicine during pregnancy
  • If you could become pregnant, you must use effective contraception or abstain from penetrative sex

You should discuss your personal circumstances with your doctor if you are pregnant or want to become pregnant. This is so that together you can make a decision about what treatment you may need during your pregnancy.

You should discuss whether there are any other medicines which you could use during pregnancy which would treat your condition.

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Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Rotigotine:

  • women who are using Rotigotine should not breast-feed

Before you use Rotigotine you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could use which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

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Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's appearance and to make it easier to use. Some may be used to prolong the life of the medicine.

This medicine contains rotigotine.

We are unable to list all of the ingredients for your medicine here. For a full list, you should refer to the patient information leaflet that comes with this medicine. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies. You should also check whether any of these ingredients are known to have side-effects.

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Rotigotine before, do not take Rotigotine. Talk to your prescriber, pharmacist or nurse as soon as possible.

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Rotigotine, Version 15, last updated 05 Jan 2015