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The eMC  

Last Updated 29 Jul 2015

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Glycopyrronium bromide powder for solution for iontophoresis

Glycopyrronium bromide (Gly-ko-pir-row-nee-um broh-mide) is a medicine which is used in chronic obstructive pulmonary disease, drying secretions before general anaesthesia, excessive sweating, preventing slow heart rate during general anaesthesia and reversal of a neuromuscular block.

The information in this Medicine Guide for Glycopyrronium bromide varies according to the condition being treated and the particular preparation used.

Glycopyrronium bromide powder for solution for iontophoresis

Information specific to Glycopyrronium bromide powder for solution for iontophoresis when used in Sweating

Your medicine

Glycopyrronium bromide belongs to a class of medicines called antimuscarinics (an-tee-musk-ar-in-iks). It is used to treat excessive sweating.

Antimuscarinics like Glycopyrronium bromide, work by blocking the effects of a chemical called acetylcholine (ass-it-yl-koh-leen). One of the effects of acetylcholine is to regulate sweating. By blocking the effects of acetylcholine in areas of the body that sweat too much, the sweating can be reduced.

Glycopyrronium bromide needs to be dissolved in water and then delivered through the skin using a special machine called an iontophoresis machine (i-on-toe-for-ee-sis). Your prescriber will arrange treatment sessions for you or tell you how to perform your own treatments at home.

Other information about Glycopyrronium bromide:

  • if you are having treatment with Glycopyrronium bromide and it has had some side-effects, you must avoid over-exertion until all the side-effects have resolved. Because Glycopyrronium bromide decreases sweating, it may make you prone to overheating from over-exertion, especially in hot weather

Glycopyrronium bromide is usually given to you by a healthcare professional. The person responsible for giving you your medicine will make sure that you get the right dose.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber or someone involved in your medical care.

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When to take your medicine

The person with responsibility for giving you your medicine will make sure that you have your medicine at the prescribed times.

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How to take your medicine

This medicine will be given to you by a member of the medical team. If you have any concerns about this medicine or how this will be given to you, talk to someone who is involved in your medical care.

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Taking too much of your medicine

Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice.

Contact your prescriber, pharmacist, specialist clinic or call 111 for advice.

Make sure you take all of your medicine containers with you if you are advised to go to hospital.

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Stopping your medicine

If you are not having any problems with this medicine, you may keep using it until you no longer need it or your prescriber advises you to stop using it.

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Looking after your medicine

The medical team will often be responsible for looking after this medicine. However, if you are responsible for looking after this medicine make sure that you store it properly and safely. Check the label and Patient Information leaflet for details or ask a member of your medical team.

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Whether this medicine is suitable for you

Glycopyrronium bromide is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

Over time it is possible that Glycopyrronium bromide can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Glycopyrronium bromide has become unsuitable, it is important that the prescriber is contacted immediately.

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A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

The frequency of these side-effects is unknown

  • blurred vision
  • difficulties urinating
  • difficulty eating
  • faster heart rate
  • feeling drowsy
  • stomach discomfort
  • tingling of the skin during treatment

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.

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Taking other medicines

There are no known important interactions between Glycopyrronium bromide and other medicines. If you experience any unusual symptoms while using Glycopyrronium bromide and other medicines you should tell your prescriber.

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Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Glycopyrronium bromide.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Glycopyrronium bromide:

  • this medicine could affect your ability to drive or operate machinery

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

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Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Glycopyrronium bromide:

  • there are no specific foods that you must exclude from your diet when using Glycopyrronium bromide
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Alcohol can interact with certain medicines.

In the case of Glycopyrronium bromide:

  • there are no known interactions between alcohol and Glycopyrronium bromide
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Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Glycopyrronium bromide:

  • do not use this medicine during pregnancy

You should discuss your personal circumstances with your doctor if you are pregnant or want to become pregnant. This is so that together you can make a decision about what treatment you may need during your pregnancy.

You should discuss whether there are any other medicines which you could take during pregnancy which would treat your condition.

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Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

For information about Glycopyrronium bromide and breast-feeding, contact your prescriber.

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Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's appearance and to make it easier to use. Some may be used to prolong the life of the medicine.

This medicine contains glycopyrronium bromide.

We are unable to list all of the ingredients for your medicine here. For a full list, you should refer to the patient information leaflet that comes with this medicine. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies. You should also check whether any of these ingredients are known to have side-effects.

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Glycopyrronium bromide before, do not take Glycopyrronium bromide. Talk to your prescriber, pharmacist or nurse as soon as possible.

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Glycopyrronium bromide, Version 8, last updated 29 Jul 2015