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The eMC  

Last Updated 12 Jan 2015

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Ofloxacin 0.3% eye drops

Ofloxacin (Off-lox-ass-in) is a medicine which is used in bacterial eye infections and bacterial infections.

The information in this Medicine Guide for Ofloxacin varies according to the condition being treated and the particular preparation used.

Ofloxacin 0.3% eye drops

Information specific to Ofloxacin 0.3% eye drops when used in bacterial eye infections

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Your medicine

Ofloxacin is used to treat eye infections caused by certain types of bacteria. When Ofloxacin is used as an eye drop it may still be absorbed into the body and therefore side effects that occur with the oral preparation of Ofloxacin may occur.

Other information about Ofloxacin:

  • if you wear contact lenses you should check with your prescriber if you can use this medicine while wearing contact lenses
  • Ofloxacin can make your skin more sensitive to sunlight. You should avoid unnecessary exposure to sunlight or any sources of UV rays while using Ofloxacin
  • this medicine should not be used for more than 10 days. If your symptoms continue or become worse you should contact your doctor

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should use. It also tells you how often you should use your medicine. This is the dose that you and your prescriber have agreed you should use. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

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When to take your medicine

Some medicines work best if they are taken at a specific time of day. Getting the most from your medicine can also be affected by the times at which you take other medicines.

Specific information on when to use Ofloxacin can be found in the Patient Information Leaflet that comes with this medicine. Alternatively, you can request information about when to take your medicine from your doctor or pharmacist.

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How to take your medicine

Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine.

Specific information on how to use Ofloxacin can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to take your medicine from your doctor or pharmacist.

If you are having problems taking this form of Ofloxacin, you should talk to your prescriber or pharmacist. They may be able to give you advice on other ways to take your medicine or other preparations that are easier for you to take.

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Taking too much of your medicine

Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. This is because the effects of taking too much medicine are very complex so it is very important that you seek medical advice.

Contact your prescriber, pharmacist, specialist clinic or call 111 for advice.

Make sure you take all of your medicine containers with you if you are advised to go to hospital.

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Stopping your medicine

If you are not having any problems with this medicine, do not stop using it unless you have completed the course or you are advised to stop using it by your prescriber.

If you are in any doubt, contact your prescriber, pharmacist, specialist clinic or call 111.

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Looking after your medicine

The instructions on how you should keep your medicine are on the pharmacy label. It is a good idea to keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children.

Specific information on how to look after Ofloxacin can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to look after your medicine from your doctor or pharmacist.

You must not take the medicine after the expiry date shown on the packaging. If you have any unused medicine, return it to your pharmacist who will dispose of it safely.

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Whether this medicine is suitable for you

Ofloxacin is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for an infant who is under the age of one year.

Over time it is possible that Ofloxacin can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Ofloxacin has become unsuitable, it is important that the prescriber is contacted immediately.

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A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Common: More than 1 in 100 people who use Ofloxacin:

  • eye discomfort or irritation

Very rare: Fewer than 1 in 10,000 people who use Ofloxacin:

  • hypersensitivity reactions including angioedema, breathing difficulties, swelling of the throat or tongue, anaphylactic reaction or shock, itching of the eye or the eyelids - some of these may be fatal. Seek medical advice if you have breathing difficulties, angioedema of the throat or face, urticaria, itching or loss of consciousness

The frequency of these side-effects is unknown:

  • a feeling of something in the eye
  • blurred vision
  • dry eye
  • ECG changes
  • eye pain
  • feeling dizzy
  • heart problems
  • increased tear production
  • nausea
  • oedema of the eye
  • other eye or eyesight problems
  • overgrowth of micro-organisms that are not affected by Ofloxacin
  • over-sensitivity to light
  • red eye
  • Stevens-Johnson syndrome
  • swelling around the eyes
  • worsening of eye infections - seek medical advice if this happens

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.

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Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following types of medicine may interact with Ofloxacin:

If you are taking Ofloxacin and one of the above types of medicines, make sure your prescriber knows about it.

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Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Ofloxacin.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Ofloxacin:

  • after putting Ofloxacin into your eye you may have blurred vision for a short time

You must not drive or operate machinery unless your vision has returned to normal after using Ofloxacin.

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Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Ofloxacin:

  • there are no specific foods that you must exclude from your diet when using Ofloxacin
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Alcohol can interact with certain medicines.

In the case of Ofloxacin:

  • there are no known interactions between alcohol and Ofloxacin
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Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Ofloxacin:

  • the use of this medicine during pregnancy is not recommended

Careful consideration needs to be given to the risks and the benefits of using this medicine during pregnancy.

You need to discuss your specific circumstances with your doctor to make a decision about whether you are going to take this medicine during pregnancy. You should only take this medicine during pregnancy if your doctor thinks you need to take it. If the decision is that you should not have Ofloxacin, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

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Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Ofloxacin:

  • women who are using Ofloxacin should not breast-feed

Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

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Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's appearance and to make it easier to use. Some may be used to prolong the life of the medicine.

This medicine contains ofloxacin.

We are unable to list all of the ingredients for your medicine here. For a full list, you should refer to the patient information leaflet that comes with this medicine. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies. You should also check whether any of these ingredients are known to have side-effects.

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Ofloxacin before, do not take Ofloxacin. Talk to your prescriber, pharmacist or nurse as soon as possible.

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Ofloxacin, Version 15, last updated 12 Jan 2015