Last Updated 20 Jun 2007
Methysergide maleate (Meth-iss-er-jyde mal-ee-ate) is a medicine which is used in carcinoid syndrome and preventing certain types of headaches.
The information in this Medicine Guide for Methysergide maleate varies according to the condition being treated and the particular preparation used.
Methysergide maleate has been prescribed for your current medical problems and should not be used for other medical problems. Do not share your medicine with other people as it may not be suitable for them and could cause them harm. In the same way, you should not use medicines that belong to other people.
The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often to take your medicine. This is the dose that you and your prescriber have agreed you should take. Depending on your response to the medicine, how the medicine works and the goals of your treatment, your prescriber may vary your dose. You should not change the dose of your medicine unless you are told to do so by your prescriber.
Methysergide maleate is used to prevent certain types of headaches such as migraines and cluster headache. These types of headaches are known as vascular headaches. In vascular headaches the blood vessels in the head swell and cause pain. Methysergide maleate helps to stop these blood vessels from becoming swollen by blocking some of the effects of a chemical called serotonin which is found in the body.
Methysergide maleate can also be used to treat the diarrhoea which occurs in carcinoid syndrome. In carcinoid syndrome there is a high level of serotonin in the blood and this causes diarrhoea. Methysergide maleate blocks some of the effects of the high level of serotonin reducing diarrhoea.
Other information about Methysergide maleate:
Some medicines work best if they are taken at a specific time of day. Getting the most from your medicine can also be affected by what you eat, when you eat and the times at which you take other medicines. Make sure you follow any specific instructions given to you by your prescriber or that are in the Patient Information Leaflet that comes with this medicine.
Some medicines have specific instructions about how to take them. This is because they work better when taken correctly. These instructions can include getting the right dose and special instructions for preparing the medicine. Make sure you follow any specific instructions given to you by your prescriber or that are in the Patient Information Leaflet that comes with this medicine.
If you are having problems taking this medicine, you should talk to your prescriber or pharmacist. They may be able to give you advice on other ways to take your medicine or other medicines that are easier for you to take.
Taking extra doses of some medicines can be harmful. In some cases even one extra dose can cause you problems. If you take extra doses of your medicine, you must get medical advice immediately. You may need a test to assess the effect of taking extra doses. This is because the effects of taking too much medicine are very complex and it is therefore essential that you seek medical advice.
If you are not having any problems taking this medicine then do not stop taking it, even if you feel better, unless advised to do so by your prescriber. If, however, you find that this medicine is causing you problems then you should talk to your prescriber about your concerns.
If your medical team decides that it is best that you do not take this medicine any more, they may advise that you do not stop Methysergide maleate abruptly. This is because, in some instances, stopping Methysergide maleate abruptly can cause withdrawal symptoms or cause your original condition to return. In these instances, reducing the dose of Methysergide maleate gradually over time may reduce the chances of having these problems.
The instructions on how you should keep your medicine are on the pharmacy label. It is a good idea to keep your medicine in the original container. This will help to keep your medicine in the best condition and also allow you to check the instructions. Do not take the medicine if the packaging appears to have been tampered with or if the medicine shows any signs of damage. Make sure that the medicine is out of the sight and reach of children.
Specific information on how to look after Methysergide maleate can be found in the Patient Information Leaflet that comes with this medicine or on the medicine label. Alternatively, you can request information about how to look after your medicine from your doctor or pharmacist.
Methysergide maleate is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.
Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.
Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.
If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.
The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.
Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.
Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.
Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.
When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.
Like all medicines Methysergide maleate can cause side effects. You should see how this medicine affects you and then judge if you are safe to drive or operate machinery. If you are in any doubt, talk to your prescriber.
Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.
In the case of Methysergide maleate:
If you are planning to become pregnant, you should discuss your personal circumstances with your doctor so that together you can make a decision about what treatment you may need during your pregnancy.
Certain medicines can pass into breast milk and may reach your baby through breast-feeding.
In the case of Methysergide maleate:
Before you have your baby you should discuss breast-feeding with your doctor or midwife. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.
Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine's taste and appearance and to make it easier to take. Some may be used to prolong the life of the medicine.
This medicine contains methysergide maleate.
We are unable to list all of the ingredients for your medicine here. For a full list, you should refer to the patient information leaflet that comes with this medicine. You should check that you are able to take the ingredients of your medicine, especially if you have any allergies. You should also check whether any of these ingredients are known to have side-effects.
If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Methysergide maleate before, do not take Methysergide maleate. Talk to your prescriber, pharmacist or nurse as soon as possible.
Methysergide maleate, Version 1, last updated 20 Jun 2007