Patient Information Leaflet
last updated on the eMC:
27/02/2012
When a pharmaceutical company changes an SPC or PIL, a new version is published on the eMC. For each version, we show the dates it was published on the eMC and the reasons for change.
Updated on 27/02/2012 and displayed until Current
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Reasons for adding or updating:
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Change to how the medicine works
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Change to Further Information section
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Change to date of revision
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Correction of spelling/typing errors
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Change to warnings or special precautions for use
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Change of contra-indications
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Change to storage instructions
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Change to side-effects
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Change to drug interactions
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Updated on 09/01/2012 and displayed until 27/02/2012
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Reasons for adding or updating:
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Change/addition of instructions for reconstitution and/ or administration
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Change to, or new, use for medicine
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Change to dosage and administration
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Updated on 13/09/2011 and displayed until 09/01/2012
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Reasons for adding or updating:
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Change to drug interactions
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Updated on 17/01/2011 and displayed until 13/09/2011
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Reasons for adding or updating:
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Change to warnings or special precautions for use
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Change to drug interactions
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Updated on 14/09/2010 and displayed until 17/01/2011
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Reasons for adding or updating:
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Change to warnings or special precautions for use
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Change to side-effects
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Change to dosage and administration
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Updated on 24/02/2009 and displayed until 14/09/2010
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Reasons for adding or updating:
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Change to date of revision
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Change to drug interactions
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Updated on 12/05/2008 and displayed until 24/02/2009
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Reasons for adding or updating:
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Transfer to upgraded management system
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Updated on 21/02/2008 and displayed until 12/05/2008
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Reasons for adding or updating:
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Change to warnings or special precautions for use
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Change of contra-indications
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Change to drug interactions
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Change to date of revision
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Updated on 25/07/2007 and displayed until 21/02/2008
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Reasons for adding or updating:
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Change of contra-indications
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Change to drug interactions
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Change to warnings or special precautions for use
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Change to Further Information section
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Change to date of revision
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PIL Retired combination of strengths
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Updated on 14/06/2007 and displayed until 25/07/2007
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Reasons for adding or updating:
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Change to, or new, use for medicine
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Change to warnings or special precautions for use
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Change to side-effects
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Change to Further Information section
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Change to date of revision
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Improved Electronic Presentation
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Change to dosage and administration
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Change to how to administer the medicine
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Change of special precautions for disposal
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Updated on 26/09/2006 and displayed until 14/06/2007
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Reasons for adding or updating:
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Change to manufacturer contact details
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Updated on 07/08/2006 and displayed until 26/09/2006
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Reasons for adding or updating:
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Change to drug interactions
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Updated on 28/07/2006 and displayed until 07/08/2006
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Reasons for adding or updating:
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PIL Retired pending re-submission
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Change to drug interactions
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Updated on 01/03/2006 and displayed until 28/07/2006
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Reasons for adding or updating:
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Change to, or new, use for medicine
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Change of contra-indications
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Change to side-effects
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Change to Further Information section
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Change to warnings or special precautions for use
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Change to dosage and administration
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Updated on 31/05/2005 and displayed until 01/03/2006
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Reasons for adding or updating:
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New PIL for eMC ie a PIL for an existing product but one that is new to the eMC
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